App News: Ultra-fast Multiplexed Online SPE-LC-MS/MS System for the Simultaneous Analysis of Drugs in Human Plasma

Ultra-Fast Multiplexed Online SPE-LC-MS/MS

High-throughput drug analysis doesn’t have to mean longer run times or complex sample prep. This application note shows how a 4-channel multiplexed online SPE-LC-MS/MS system enables automated cleanup, continuous MS operation, and rapid analysis of drugs in human plasma—delivering a cycle time of just 3.7 minutes per sample while maintaining excellent quantitative performance

In this application note, you’ll see how:

• Multiplexed LC-MS/MS nearly doubles sample throughput
• Integrated online SPE reduces matrix effects and manual handling
• Low-hydrophobicity drugs are analyzed simultaneously and accurately
• High linearity and QC accuracy are achieved across 17 drugs

Download the app news to explore the workflow, system setup, and real performance data.