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LCMS-2050 Single Quad

The walk-up-ready mass spec your chemists will actually want to use

The LCMS-2050 combines mass-directed purification, high-sensitivity detection, and everyday ease-of-use in one compact powerhouse instrument. Built for the high-throughput realities of discovery and synthesis workflows, it fits neatly into your existing stack and handles tens of thousands of samples a year without breaking a sweat.

Whether you’re verifying small-molecule synthesis, purifying nucleic acids, or supporting ADME studies, the LCMS-2050 gives your team the performance they need.



Power and Energy Efficient:

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Meet the LCMS-2050


LCMS-2050 is a Perfect Fit for:

  • Med chem and formulation teams in discovery
  • CROs and biotechs developing cutting-edge therapeutics
  • Purification labs needing precise, mass-based control
  • Any lab looking to save money and bench space!
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Why Labs Choose the LCMS-2050

  • Ease of Use – Seamlessly integrates with Shimadzu’s Open Solutions software for walk-up access. Great for labs with multiple users of varying skill levels.
  • High Sensitivity – Detect low-abundance compounds with the performance of much larger systems.
  • Built for Throughput – Trusted by labs processing tens of thousands of samples per year.
  • Rock-Solid Reliability – Engineered for robustness and long runtimes even under heavy use.
  • Low Operating Costs – Delivers 43% energy savings compared to previous models to reduce overall cost of ownership.

Ready to Separate Yourself from the Competition?

Discover how the LCMS-2050 can streamline your discovery workflow and help your team do more with less.